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Piso, B. and Mathis, S. (2010): Kyphoplasty and vertebroplasty for osteoporotic vertebral compression fractures. Decision Support Document 08/Update 2010.

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In addition to the studies includes in the MEL report of 2008, we identified nine recent studies assessing benefits and harms of both interventions for this update. The evidence for benefits of kyphoplasty compared to conservative treatment increased based on the results of the first randomised controlled trial (RCT). In contrary to non randomised studies and RCTs comparing vertebroplasty with conservative treatment, results of two recent placebo controlled RCTs showed no advantage of vertebroplasty over a placebo intervention. For the direct comparison of both interventions there are still no RCTs available.

Item Type:Decision Support Document
Keywords:Osteoporosis, brittle bone syndrome, vertebral compression fractures, traumatic compression fractures, elderly, percutaneous vertebroplasty, balloon kyphoplasty, balloon-assisted, minimally invasive procedures, Medtronic (Kyphon), bone cement, pain, pain relief, agility, quality of life
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WE Musculoskeletal system > WE 720-755 Back
WE Musculoskeletal system > WE 200-259 Bones
WE Musculoskeletal system > WE 168-190 Orthopedics
Series Name:Decision Support Document 08/Update 2010
Deposited on:14 Jul 2010 17:34
Last Modified:15 Jul 2020 17:44

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