Radiofrequency ablation (RFA) is a relatively new, minimally-invasive ablation method that destroys tumours by local application of heat.
In terms of RFA for the treatment of lung tumours, we included one randomised controlled trial and ten prospective case-series. According to GRADE, the quality of evidence of the included RCT is very low due to major methodological flaws. Moreover, the quality of evidence of the included case-series is very low due their uncontrolled study design. Overall, the available evidence is insufficient to assess the efficacy and safety of RFA compared to the respective standard therapy for the treatment of lung tumours. Furthermore, there is no evidence regarding RFA for the treatment of tumours of mediastinal lymph nodes.