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Erdos, J. and Ibargoyen Roteta, N. and Gutiérrez Ibarluzea, I. (2017): Repetitive transcranial magnetic stimulation for treatment-resistant major depression. Decision Support Document 107.

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Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation technique indicated for patients with treatment-resistant unipolar major depression (TRD). The stimulation is carried out by a coil that is placed on the scalp and delivers brief magnetic pulses.

We evaluated the efficacy and safety of high-frequency stimulation to the left dorsolateral prefrontal cortex compared to sham stimulation, as well as to electroconvulsive therapy.

The current evidence indicates that rTMS is more effective than and as safe as sham, but it is not sufficient to prove that it is as effective and safe as ECT. Due to the low quality of evidence we recommend rTMS for patients with TRD with restrictions.

Item Type:Decision Support Document
Keywords:Repetitive transcranial magnetic stimulation (rTMS), major depression, treatment-resistant depression (TRD), high-frequency rTMS, electroconvulsive therapy (ECT)
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WM Psychiatry > WM 170-197 Neurotic disorders > WM 171 Depression. Depressive Disorder
Series Name:Decision Support Document 107
Deposited on:17 Jul 2017 10:03
Last Modified:15 Jul 2020 17:56

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