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Erdos, J. and Fischer, S. (2018): High-intensity focused ultrasound for the treatment of prostate cancer. 1st Update 2018. Decision Support Document 37/ Update 2018.

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Prostate cancer is one of the most common cancer types in men in Europe. We reviewed current evidence on efficacy and safety of high-intensity focused ultrasound (HIFU) as primary or salvage therapy compared to radiotherapy, active surveillance, watchful waiting, and radical prostatectomy in the treatment of low and intermediate-risk localised or locally recurrent prostate cancer.

To assess efficacy, one controlled study was evaluated that compared primary HIFU with brachytherapy (a type of radiotherapy) in the treatment of localised prostate cancer. No other controlled trials comparing primary or salvage HIFU with other treatment modalities could be identified. To assess safety, in addition to the controlled study, five prospective case series were evaluated.

The current evidence is insufficient to demonstrate the efficacy and safety of both primary and salvage HIFU compared to other interventions. On the basis of the limited evidence, the inclusion in the BMG catalogue of procedures is currently not recommended.

Item Type:Decision Support Document
Keywords:Prostate cancer, high-intensity focused ultrasound, ablation therapy, non-invasive surgery
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
WB Practice of medicine > WB 515 Ultrasonic therapy
WJ Urogenital system > WJ 700-875 Male genitalia
WJ Urogenital system > WJ 140-160 Urologic diseases
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
QZ Pathology > QZ 200-380 Neoplasms.Cysts
WO Surgery > WO 505 Minimally invasive surgical procedures
Series Name:Decision Support Document 37/ Update 2018
Deposited on:20 Jul 2018 09:53
Last Modified:15 Jul 2020 17:58

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