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Rosian, K. and Stanak, M. (2018): Lymphovenous anastomoses in patients with primary and secondary lymphoedema. Decision Support Document 110.

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Lymphoedema is a chronic disease that may be congenital (primary) or acquired (secondary). Without appropriate treatment, lymphoedema leads to pain and an impaired quality of life. We investigated the efficacy and safety of lymphovenous anastomoses (LVA), a minimally invasive supermicrosurgical procedure, in patients with primary and secondary lymphoedema.

One non-randomised controlled study and four prospective single-arm studies were evaluated. Overall, the level of evidence is "very low" for the outcomes of clinical effectiveness and safety. Based on the available evidence, no conclusions can be drawn as to whether the assessed procedure of LVA is at least as effective and safer as the comparator VLNT or conservative therapy.

Therefore, we currently do not recommend the inclusion of LVA in the Austrian catalogue of procedures and suggest a re-evaluation after 2021, provided that the ongoing studies report patient-related outcomes.

Item Type:Decision Support Document
Keywords:Lymphovenous anastomosis, primary and secondary lymphoedema, minimally invasive procedure, quality of life, supermicrosurgery
Subjects:W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WH Hemic and lymphatic systems
WO Surgery > WO 505 Minimally invasive surgical procedures
WE Musculoskeletal system > WE 800-890 Extremities and podiatry
Series Name:Decision Support Document 110
Deposited on:20 Jul 2018 09:47
Last Modified:15 Jul 2020 17:58

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