AIHTA - Publications - Search - Intrauterine ultrasound-guided transcervical radiofrequency ablation

Lambert, R. and Strohmaier, C. (2020): Intrauterine ultrasound-guided transcervical radiofrequency ablation. Decision Support Document 120.

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Myomas of the uterus are the most common benign neoplasms in the female pelvis. In addition to the definitive removal of the uterus (hysterectomy) or uterus-preserving procedures (Myomectomy, MRgFUs, UAO, UAE, USgFUS/USgHIFU), intrauterine ultrasound-guided transcervical radiofrequency ablation (TFA) is another uterus-preserving, mostly in the outpatient setting conducted intervention for myomas. In TFA, radiofrequency energy (RF) is used to cause coagulative necrosis of the tissue to reduce the volume and associated symptoms of uterine leiomyomas.

No comparative studies were identified in the course of the search strategy. The study pool for the evaluation of evidence consisted of three prospective single-arm studies (234 patients), which were published in seven publications. The quality of the evidence regarding efficacy and safety was rated as low or very low for all relevant endpoints.

Inclusion in the Austrian benefit catalogue is currently not recommended. Due to the low quality of the evidence, comparative studies of TFA in symptomatic myomas are necessary in order to make a reliable statement regarding clinical efficacy and safety.

Item Type:Decision Support Document
Keywords:Radiofrequency ablation, uterine leiomyoma, myoma ablation, myoma therapy
Subjects:W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WA Public health > WA 309 Women´s health
WB Practice of medicine > WB 300-962 Therapeutics
WB Practice of medicine > WB 515 Ultrasonic therapy
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WO Surgery > WO 505 Minimally invasive surgical procedures
WP Gynaecology > WP 440-468 Uterine diseases
Series Name:Decision Support Document 120
Deposited on:15 Jul 2020 10:47
Last Modified:15 Jul 2020 18:02

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