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Gassner, L. (2021): Implantation of Bulking Agents for Faecal Incontinence. Update 2021. Decision Support Document 87/1.

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This systematic review aims to evaluate whether implantable bulking agents are superior or inferior to injectable bulking agents as second-line therapy in terms of clinical effectiveness and safety for faecal incontinence (FI). Six prospective uncontrolled trials were included. FI severity significantly improved sustainably, but not disease-related quality of life. Procedure-related adverse events hardly occurred. In nearly one quarter dislodgement of prostheses occurred. Studies were judged with moderate to high risk of bias and the strength of evidence for safety was judged to be very low. Implantable bulking agents might be a minimally invasive approach in FI treatment if conservative therapies fail.

Item Type:Decision Support Document
Keywords:Faecal incontinence, bulking agents, Gatekeeper, Sphinkeeper, Systematic review
Subjects:W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WB Practice of medicine > WB 300-962 Therapeutics
WI Digestive system > WI 600-650 Anus. Rectum
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WO Surgery > WO 505 Minimally invasive surgical procedures
Series Name:Decision Support Document 87/1
Deposited on:15 Jul 2021 07:27
Last Modified:15 Jul 2021 07:27

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