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Walter, M. and Gassner, L. (2021): Liposuction for surgical therapy of lipoedema. Decision Support Document 125.

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Lipoedema is a painful, chronic and progressive fat distribution disorder of the extremities. If conservative therapy does not result in sufficient improvement of symptoms, a surgical intervention, liposuction under tumescence anaesthesia, may be indicated. We investigated the clinical effectiveness and safety of liposuction for surgical therapy of lipoedema (stage I-III).

No comparative evidence could be identified. Six prospective and one additional retrospective single-arm before/after studies were evaluated. The current evidence suggests that liposuctions lead to a significant pain reduction and improved health-related quality of life. However, the studies have several limitations. Overall, the quality of evidence for clinical effectiveness is not estimable and "very low" for safety outcomes.

Inclusion in the Austrian benefit catalogue is currently not recommended. Robust comparative studies of liposuction for lipoedema are necessary in order to make a reliable statement regarding clinical effectiveness and safety.

Item Type:Decision Support Document
Keywords:Liposuction, lipoedema, fat distribution disorder, tumescent anaesthesia, systematic review
Subjects:W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WA Public health > WA 309 Women´s health
WB Practice of medicine > WB 300-962 Therapeutics
WD Disorders of systemic, metabolic or environmental origin > WD 200-226 Metabolic diseases
WE Musculoskeletal system > WE 800-890 Extremities and podiatry
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WO Surgery > WO 600-640 Plastic surgery
Series Name:Decision Support Document 125
Deposited on:15 Jul 2021 07:27
Last Modified:15 Jul 2021 07:27

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